Initial characterization of a human megakaryocytic leukemia cell line, EST-IU. Sledge GW Jr, Roth BJ, Heerema NA, Glant M, Jansen J, Goheen M, Hoffman R. PMID: 3725784 [PubMed - indexed for MEDLINE] MeSH Terms. Antigens, Surface; Cell Line; Humans; Megakaryocytes/immunology; Megakaryocytes/metabolism; Megakaryocytes/pathology; Peroxidases/metabolism; Phenotype
Abbreviations ACP — acid phosphatase ADCC — antigen-dependent cell-mediated cytotoxicity ALL — acute lymphoblastic leukemia ALP — alkaline phosphatase AML — acute myeloid leukemia ANAE — α-naphthylacetate esterase ANBE — α-naphthylbutyrate esterase AraC — cytosine arabinoside ATCC — American Type Culture Collection ATRA — all-trans retinoic acid AUL — acute
To date, the function of autophagy in cell differentiation is poorly documented. Here, we investigated the possibility that megakaryocytic differentiation of the Chronic Myelogenous Leukemia (CML) cell line K562, a process known to be accompanied by accumulation of vacuoles inside the cells, might involve autophagy. Acute megakaryoblastic leukemia. Patients with acute megakaryoblastic leukemia usually have cytopenias, although some may have thrombocytosis. Dysplastic features are often present in all cell lines. Diagnosis requires the presence of at least 20% blasts, of which at least 50% must be of megakaryocyte origin.
platelets, into the circulation. Summary. A new megakaryoblastic cell line (CMK), which also exhibits erythroid and myeloid markers, was established from a Down's syndrome patient suffering from acute megakaryoblastic leukaemia. The CMK cells were found to be positive in reactions with anti‐platelet antibodies (anti‐glycoproteins IIb/IIIa and Ib, and Plt‐1).
Pediatr production of myeloid cells like erythrocytes, megakaryocytes, neutrophils and monocytes.
Hairy cell leukemia (HCL) is a rare tumor disease that originates from the B myeloid leukaemia) bone marrow is usually seen as small megakaryocytes with are derived from pluripotent hematopoietic stem cells that undergo lineage,
According to the Nati Leukemia is a certain type of cancer, specifically a cancer of the blood cells. This is where abnormal white blood cells are produced in the bone marrow, and they begin to take over the production of red blood cells, overcrowding and leadi Leukemia is cancer of the white blood cells. There are two types of Leukemias, acute and chronic.
on megakaryocytic leukemia cell lines have not been reported. In this study, four human megakaryocytic leukemia cell lines were chosen to examine the potential induction of apop-tosis by As 2 O 3. HEL and Meg-01 are growth factor inde-pendent [13,14], and two other megakaryocytic cell lines, UT7 and M07e, are growth factor dependent [15,16]. The
on megakaryocytic leukemia cell lines have not been reported. In this study, four human megakaryocytic leukemia cell lines were chosen to examine the potential induction of apop-tosis by As 2 O 3. HEL and Meg-01 are growth factor inde-pendent [13,14], and two other megakaryocytic cell lines, UT7 and M07e, are growth factor dependent [15,16]. The Fig 4. Transmission electron micrograph of Dami cells after 8 months in culture.
Celllinjekulturer och in vitro- bedömning av prednisolonsensibiliserande effekter Ara-C in primary AML 29 and Acute Megakaryocytic Leukemia (AMkL) cells.
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B- and T-lymphocytes, natural killer cells, granulocytic cells and megakaryocytic cells. av GL Norddahl · 2011 · Citerat av 190 — Mitochondria numbers change in a stage- and lineage-specific manner to bipotent megakaryocytic/erythroid precursor cells (pre Meg/Es) but On the last day of culture, cells were harvested and stained with Research Council, the Swedish Pediatric Leukemia Foundation, and the Crafoord Foundation. Cancer Cell Lines: Part 3: Leukemias and Lymphomas: Palsson, Bernhard Ø: This book describes all human leukemia-lymphoma cell lines that have been T-lymphocytes, natural killer cells, granulocytic cells and megakaryocytic cells.
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16 May 2019 JAK inhibitors are selective for acute megakaryoblastic leukemia and We validated a panel of 8 AML cell lines derived from children and
Here, we investigated the possibility that megakaryocytic differentiation of the Chronic Myelogenous Leukemia (CML) cell line K562, a process known to be accompanied by accumulation of vacuoles inside the cells, might involve autophagy. Megakaryocytic differentiation of leukemie cell line, MC3, by phorbol ester 941 The promoter region of the gene encoding GPIIb has been previously analyzed to determine its tissue-specific transcriptional activity and was shown to contain a tissue-specific enhancer which is active in both erythroid and megakaryocytic lineages [22-25].
A new human megakaryocytic cell line (Dami) has been established from the blood of a patient with megakaryoblastic leukemia. The Dami cells grow primarily in suspension with a doubling time of 24 to 30 hours.
In contrast, As2O3 at similar concentrations had no effects on either viability or growth of the nonmegakaryocytic leukemia cell line HL60 and two human breast cancer cell lines, ZR75 and MCF7. The acute myeloid leukemia (AML)-derived cell lines HU-3, Flow cytometric analysis of the GM-CSF- and TPO-cultured lines displayed an up-regulation of the megakaryocytic surface markers CD41, BibTeX @MISC{Ge02downsyndrome, author = {Yubin Ge and Tanya L Jensen and Larry H Matherly and Jeffrey W Taub and Neoplasia Articles and Yubin Ge and Tanya L. Jensen and Larry H. Matherly and Jeffrey W. Taub}, title = {Down Syndrome Megakaryocytic Leukemia Cell Lines}, year = {2002}} Leukemia is a complex condition with a wide range of symptoms. By learning the signs and symptoms of this disease, you can improve the prognosis of acute leukemia and chronic leukemia. Check out these leukemia cancer facts to help you under Skip to Content Search Menu This is Cancer.Net’s Guide to Leukemia - Chronic T-Cell Lymphocytic. Use the menu below to choose the Introduction section to get started.
Neuroreport Soreq H.BuddChiari syndrome a.acute leukemia.